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Responds to comments by Stefan G. Hofmann (see record 2011-19228-003), Edward A. Wise (see record 2011-19228-004), Michael J. Lambert (see record 2011-19228-005), and William H. Gottdiener (see record 2011-19228-006) on the authors original article "Statistical significance testing and clinical trials" (see record 2011-19228-002). The original article is one very narrowly focused effort at studying the implications of relying on the null hypothesis significance test (NHST) for determining which psychotherapy randomized clinical trial (RCT) findings to take seriously for clinical purposes. Although there are several approaches for faulting the NHST, the matter is important and complicated enough to justify dealing, in detail, with one approach at a time. (PsycINFO Database Record (c) 2011 APA, all rights reserved) 相似文献
44.
中国传统建筑装饰历史悠久,艺术风格与技术手法独特,不仅具有丰富的外在形式美,而且蕴含深邃的文化意义和思想内涵。本文通过研究传统建筑装饰题材通过特殊表现手法中所隐喻的文化意涵,为进一步解读装饰语义提供参考,以揭示传统建筑审美价值和生活哲学观。 相似文献
45.
通过对类型学的论述,简单介绍建筑类型学在居住建筑中如何体现与运用,接着以菊儿胡同为例阐述上述观点,最后阐述类型学如何指导我国的建筑运动,并提出建筑设计应整体地体现五点交织的原则。 相似文献
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《Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment》2013,30(3):308-324
Contamination of grain with 1,2-dehydropyrrolizidine ester alkaloids (dehydroPAs) and their N-oxides is responsible for large incidents of acute and subacute food poisoning, with high morbidity and mortality, in Africa and in central and south Asia. Herbal medicines and teas containing dehydroPAs have also caused fatalities in both developed and developing countries. There is now increasing recognition that some staple and widely consumed foods are sometimes contaminated by dehydroPAs and their N-oxides at levels that, while insufficient to cause acute poisoning, greatly exceed maximum tolerable daily intakes and/or maximum levels determined by a number of independent risk assessment authorities. This suggests that there may have been cases of disease in the past not recognised as resulting from dietary exposure to dehydroPAs. A review of the literature shows that there are a number of reports of liver disease where either exposure to dehydroPAs was suspected but no source was identified or a dehydroPA-aetiology was not considered but the symptoms and pathology suggests their involvement. DehydroPAs also cause progressive, chronic diseases such as cancer and pulmonary arterial hypertension but proof of their involvement in human cases of these chronic diseases, including sources of exposure to dehydroPAs, has generally been lacking. Growing recognition of hazardous levels of dehydroPAs in a range of common foods suggests that physicians and clinicians need to be alert to the possibility that these contaminants may, in some cases, be a possible cause of chronic diseases such as cirrhosis, pulmonary hypertension and cancer in humans. 相似文献
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《Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment》2013,30(2):241-248
The aim of this study was to determine the levels of Penicillium citreonigrum and citreoviridin present in rice samples from Maranhão State, Brazil, where an outbreak of beriberi was reported and 32 deaths occurred (7% of the notified cases died in 2006). The ability of P. citreonigrum to produce citreoviridin was assessed, and a total of 420 samples of 21 different kinds of rice were collected. Mycobiota isolation and identification, the ability of citreoviridin strains to produce toxin, and the natural occurrence of citreoviridin were established. Rice samples were found to have high fungal counts and showed increasing levels from 2004 to 2007 harvest years. The most frequent genus was Aspergillus followed by Penicillium and Cladosporium. Ten out of eleven strains of P. citreonigrum were able to produce citreoviridin. Three rice samples had levels of citreoviridin ranging from 12 to 96.7 ng g?1, and two bran samples had levels of 128 and 254 ng g?1. These samples contaminated with P. citreonigrum and citreoviridin were involved in the beriberi cases from Maranhão State. Monitoring rice for mycotoxins in areas where this substrate is the basic food is crucial to prevent outbreaks like the one reported in this study, to improve management practice, and to diminish exposure risk of humans to these harmful toxins. 相似文献
49.
简述经评审的最低投标价法的概念,结合实际情况,阐述经评审的最低投标价法的认识,实施及其意义,并分析了实施过程中存在的问题,提出了相应的对策,以期促进有形建筑市场健康、有序的发展。 相似文献
50.
天然气水合物的资源与环境意义 总被引:7,自引:0,他引:7
天然气水合物是在低温高压环境下由水分子和气体分子构成的结晶状特殊固体化和物,它主要分布于永久冻土带及浅海大陆架及深海平原沉积物中。天然气水合物的开发利用涉及两个方面的问题:①从资源方面考虑,天然气储量巨大,能够满足人类未来清洁能源的需求;②从环境方面考虑,甲烷的释放将引发全球气候变化和一系列的海洋地质灾害。因此,在开发利用天然气水合物之前,必须有超前的防范措施,以防止天然气水合物对环境造成的不良影响。 相似文献